Guanidine hydrochloride: An efficient catalyst for the synthesis of 2-hydrazolyl-4-thiazolidinone derivatives under solvent free conditions

guanidine hydrochloride: an efficient catalyst for the synthesis of 2-hydrazolyl-4-thiazolidinone derivatives under solvent free conditions

a highly efficient protocol has been developed for the synthesis of 2-hydrazolyl-4-thiazolidinone derivatives installing a one pot three component coupling reaction of an aromatic aldehyde, thiosemicarbazide and maleic anhydride using guanidine hydrochloride as highly inexpensive and environmentally friendly catalyst under solvent free condition at 1200c with good to excellent yields, it offers...

Caro’sacid-silicagel: An Efficient and Reusable Catalyst for the Synthesis of 2, 4, 5- Trisubstituted Imidazoles under Solvent-free Conditions

Caro’s acid-silicagel was found to be a mild and effective catalyst for the one –pot multicomponent condensation of benzyl, aldehydes and ammonium acetate used for synthesis of 2, 4, 5-trisubstituted imidazole derivatives under solvent–free conditions. This catalyst has several advantages such as simple work-up, low cost and reusability.

4-Sulfobenzoic Acid as an Efficient Catalyst for the Preparation of 3,4-dihydropyrimidin-2-(1H)-ones Under Solvent-free Conditions

In this research, one-pot three-component synthesis of 3,4-dihydropyrimidin-2-(1H)-ones havebeen developed using Biginelli reaction from the interaction between ethyl/methyl acetoacetate,aromatic aldehydes, and urea/thiourea in the presence of 4-sulfobenzoic acid as a new, effective,inexpensive, and available bronsted acid. Avoidance of toxic and dangerous solvents, easy isola...

A Fast and Efficient Method for the Synthesis of 1,5-Benzodiazepine Derivatives Under Solvent-Free Conditions

Silica sulfuric acid is found to catalyze efficiently the condensation of o-phenylenediamines with various linear and cyclic ketones to afford the corresponding 1,5-benzodiazepines in quantitative yields under solvent-free conditions at room temperature

caro’sacid-silicagel: an efficient and reusable catalyst for the synthesis of 2, 4, 5- trisubstituted imidazoles under solvent-free conditions

nano-rods zno as an efficient catalyst for the synthesis of chromene phosphonates, direct amidation and formylation of amines

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